About PEW

　P.E.W , a Co-developed Technology with Tohoku University, Applying for International Patent. It is a revolutionary new way to generate Acid Electrolyzed water and Alkaline Electrolyzed water, with both functions, PEW performs its superior efficiency and safety to healthcare ,food processing and manufacturing, It is a fast working anti-microbial solution suitable for use in many industries. 

About SOWATER

　SOWATER is an international brand for products produced based on P.E.W technology. With a mission that SOWATER brings you a healthier Life, SOWATER launches series solutions for various of skin disorders, Hand hygiene, baby care,patient care, etc.

Advantage of SOWATER

1.Superior efficacy and safety

　Sowater has been clinically tested to be very efficient, it can kill 99.99% of germs,viruses and bacteria.

2.Stability

　SOWATER Performance Stabilized HOCl has been formulated to deliver maximum benefits safely throughout the life of the product.

3.Applications ：

　SKIN CARE： Red buttocks of infants, burns, allergies, prickly heat, eczema and herpes zoster;

WOUND CARE： Cleaning of abrasions or superficial small wounds, cleaning of wounds in minimally invasive surgery and wound repair ；

PERSONAL PROTECTION：Daily protection of High risk groups such as mothers, infants, children, the elderly and inpatients

Overview of HOCl

　HOCl is a weak acid that occurs naturally in our body. Neutrophils are white blood cells that are the first to arrive on site when an invading pathogen is detected. Neutrophils will chase down and engulf the pathogen through phagocytosis. Upon contact, neutrophils release a burst of bactericidal chemicals including its most powerful oxidizing agent, HOCl. This kills the pathogen by tearing down the cell membranes and proteins. That why there is a saying that Hypochlorous acid (HOCl) is the perfect weapon to fight germs.

How HOCl Kill bacteria

　A schematic representation of hypochlorous acid (HOCl) production during the oxidative burst process. During this process, cells utilize O2 and convert it to hydrogen peroxide (H2O2) using a mitochondrial-membrane–bound enzyme NADPHase. Then, myeloperoxidase catalyzes the reaction between H2O2 and Cl− to generate HOCl. As deregulations take place, the lumen of the phagasome progressively becomes more acidic and leaves the bacterium within a vacuole (phagolysosome) containing MPOse and H2O2 in a medium containing 0.1 M Cl− at estimated pH 4 to 6. During this process, conditions are optimal for MPOse-catalyzed generation of HOCl as depicted in this figure. On the basis of these principles, we set out to establish the conditions of generating the stable form of HOCl (NVC-101).

　HOCl is known to be the major strong oxidant produced by neutrophils, and is a potent microbicidal agent within these cells. Experimentally, it has been estimated that 106 neutrophils stimulated in vitro can produce 0.1 μM HOCl. This quantity of HOCl can kill 1.5 × 107 Escherichia coli in less than 5 minutes. HOCl reacts readily with a range of biological molecules, particularly those with thiol, thiolether, heme proteins, and amino groups,and may lead to tissue injury. Taurine, a nonessential amino acid naturally found at roughly 15 mM within neutrophils acts as a scavenger molecule for HOCl via the following mechanism, and effectively dampens the collateral damage to cellular macromolecules caused by HOCl

Key clinical benefits of HOCl

　Hypochlorous acid (HOCl) is a compound that is produced naturally by Neutrophils in the inmmune system to eradicate microorganisms. HOCl immediately relieves itch and pain, kills bacteria and breaks down biofilm, does not sting or irritate skin and oxygenates the cells in the area treated assisting the body in its natural healing process. Sonoma’s Performance Stabilized HOCl has been formulated to deliver maximum benefits safely throughout the life of the product.

Researches& Release

　Currently, the US Environmental Protection Agency (EPA) has recommended numerous disinfectants against COVID-19 including hypochlorous acid (HOCl). The mechanism of disinfection involves the destroying of the cell wall of microbes or viruses, allowing the disinfectant to destroy or inactivate them.

More researches proved the efficiency of HOCl

Hypochlorous Acid (HOCl): An Important Emerging Option for Periprocedural Care